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🕵️‍♂️慢性炎症:👨‍🔬維生素 D 水平低可能是一個可能的原因😻 😼

🥷🏻慢性炎症:維生素 D 水平低可能是一個可能的原因👨‍🍼 🙇‍♀️

慢性炎症與炎症相關的健康狀況有關,包括癌症、糖尿病和心血管疾病。🤳🏽

血液中升高的炎症生物標誌物如 C 反應蛋白可能是慢性炎症的指標。

一項新的研究發現血液中維生素 D 水平低與 C 反應蛋白升高之間存在聯繫。

研究人員建議,對於缺乏維生素 D 的人,提高維生素 D 水平可能會減少慢性炎症。🤳🏽

🙇 炎症是機體免疫細胞對損傷或感染的反應而激活。

在短期內,炎症是正常癒合所必需的。然而,當它持續存在時,它可能會導致與炎症相關的健康狀況的發展,例如心髒病、糖尿病和癌症等。🤳🏽

慢性炎症 可能由持續感染、接觸刺激物和自身免疫性疾病引起。但其他因素,如年齡、壓力和飲食也可能起作用。識別慢性炎症可能具有挑戰性,但血液中的特定炎症生物標誌物可以表明它的存在。其中之一是 C-反應蛋白 (CRP)。

根據 2021 年的研究,維生素 D 已被證明具有強大的抗炎作用,缺乏這種營養素可能會導致慢性炎症。

然而,維生素 D 和 CRP 之間的關聯尚不清楚。儘管先前發表在 2015 年和 2020 年可信來源的研究調查了維生素 D 對 CRP 的影響,但沒有發現支持因果關係的證據。

然而,最近發表在《國際流行病學雜誌》上的南澳大利亞大學的新基因研究發現,維生素 D 水平低與血液中 CRP 升高之間存在關聯。這一發現讓研究人員認為,在缺乏維生素 D 的人中增加維生素 D 可能會減少慢性炎症。🤳🏽

🙇‍♂️ 💁‍♀️ 💁 維生素 D 如何影響炎症?

Hyppönen 解釋說,維生素 D 是一種激素前體,可抑制炎症細胞因子如白細胞介素 12 (IL-12) 的產生。🤳🏽

“通過這樣做,它可以改變免疫反應,使 T 細胞極化從炎症型反應 (Th1) 轉變為產生更具保護性的 T 細胞表型 (Th2 和調節性 T 細胞),”Hyppönen 告訴 健康熱線。

根據這項研究,這些行動可能有助於降低炎症,從而降低許多慢性病的風險或嚴重程度。🤳🏽

💁‍♂️ 🙅‍♀️ 研究局限和未來研究

儘管研究發現維生素 D 和 CRP 之間存在關聯,但它也有一些局限性。例如,參與者是英國白人血統的人。因此,尚不清楚這些結果是否會轉移到其他種族或民族的人身上。🤳🏽

更重要的是,CRP 並不是唯一參與炎症的生物標誌物。其他生物標誌物也可能表明炎症反應,包括腫瘤壞死因子 α(TNF-α)和白細胞介素 6(IL-6)。科學家們說,進一步的研究應該檢查這些生物標誌物,以充分了解維生素 D 的抗炎作用………………………………..🤳🏽

https://www.healthline.com/health-news/chronic-inflammation-low-vitamin-d-levels-may-be-a-possible-cause?slot_pos=article_5&utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=authoritynutrition&utm_content=2022-08-23&apid=32297564&rvid=10cf1ed1e7602cd535b857949aa06030d77e5a4b3a5bcf849ff5bb15192b8b84

🙅 🙅‍♂️ Chronic inflammation is linked to inflammatory-related health conditions, including cancer, diabetes, and cardiovascular disease.

  • 🤳🏽Elevated inflammatory biomarkers in the blood like C-reactive protein can be an indicator of chronic inflammation.

  • 🤳🏽A new study has found a link between low vitamin D levels in the blood and elevated C-reactive protein.

  • 🤳🏽Researchers suggest that for people who are vitamin D deficient, improving vitamin D levels may reduce chronic inflammation.

🙆‍♀️ 🙆 Inflammation is the activation of the body’s immune cells in response to injury or infection.🤳🏽

In the short term, inflammation is necessary for proper healing. However, when it persists, it can contribute to the development of inflammatory-related health conditions such as heart disease, diabetes, and cancer, among others.

Chronic inflammationTrusted Source can result from ongoing infections, exposure to irritants, and autoimmune disorders. But other factors like age, stress, and diet may also play a role. Identifying chronic inflammation can be challenging, but specific inflammatory biomarkersTrusted Source in the blood can indicate its presence. One of which is C-reactive proteinTrusted Source (CRP).

According to 2021 research, vitamin D has been shown to have a powerful anti-inflammatory effect, and deficiencies in this nutrient may contribute to chronic inflammation.

Yet, the association between vitamin D and CRP is unclear. Although previous studies published in 2015Trusted Source and 2020Trusted Source investigated vitamin D’s influence on CRP, no evidence was found to support a causal effect.

However, new genetic research from the University of South Australia, recently published in the International Journal of Epidemiology, found an association between low vitamin D levels and elevated CRP in the blood. This discovery has researchers suggesting that boosting vitamin D in people with a deficiency may reduce chronic inflammation.🤳🏽

🙆‍♂️ 🙋‍♀️ 🙋How does vitamin D influence inflammation?

Hyppönen explained that vitamin D is a hormone precursor that inhibits the production of inflammatory cytokines such as interleukin-12 (IL-12).🤳🏽

“By doing this, it acts to modify the immune responses so that T-cell polarization moves away from an inflammatory type response (Th1) to the production of more protective T-cell phenotypes (Th2 and regulatory T-cells),” Hyppönen told Healthline.

According to the study, these actions may help to lower inflammation, thus reducing the risk or severity of many chronic diseases.🤳🏽

👨🏻 👩🏻‍🦱Study limitations and future research

Although the research found an association between vitamin D and CRP, it also had some limitations. For example, participants were individuals of white-British descent. So, it is not known if these results transfer to people of other racial or ethnic groups.🤳🏽

What’s more, CRP is not the only biomarker involved in inflammation. Other biomarkers may also indicate an inflammatory response, including tumor necrosis factor alpha (TNF-α) and interleukin 6Trusted Source (IL-6). The scientists say further investigations should examine these biomarkers to fully understand the anti-inflammatory effects of vitamin D………………..🤳🏽

https://www.healthline.com/health-news/chronic-inflammation-low-vitamin-d-levels-may-be-a-possible-cause?slot_pos=article_5&utm_source=Sailthru%20Email&utm_medium=Email&utm_campaign=authoritynutrition&utm_content=2022-08-23&apid=32297564&rvid=10cf1ed1e7602cd535b857949aa06030d77e5a4b3a5bcf849ff5bb15192b8b84